Not necessarily. It depends on the wording of the profession being relied on. Where the listing accepts a degree as an alternative to a licence, an expired licence may not decide the outcome. Where the listing is framed around a licence, it matters more. The specific listing governs.
The listing decides, not a general rule
Applicants often assume the licence is the only credential that counts because it is what their profession uses day to day. The classification is read from its own text. Counsel can confirm which route applies to the specific profession and whether the applicant's degree, transcripts, and experience satisfy it as written, rather than as it is commonly summarized.
The USMCA Appendix 2 entry for Engineer lists alternatives: a baccalaureate or Licenciatura degree, or a state, provincial or federal licence. The mismatch between the job as actually performed and the listed profession's duties, followed closely by holding a credential that is not the one the Appendix 2 entry names. Applicants who reason in the opposite direction — starting from the credential they are proudest of and looking for a listing it might fit — end up describing a job that does not match the engagement. TN eligibility still turns on Canadian or Mexican citizenship, a listed USMCA profession, its stated qualification and prearranged U.S. work; document reissuance cannot convert unrelated education into the right credential.