Not automatically. The question is whether the position, taken as a whole, remains within the listed profession the applicant qualifies for. A clinician who also oversees a small team may still fit; a role that is predominantly staff management may not. The proportions matter, so document them.
Assess the position as a whole
Officers look at what the person will do, not only the title on the offer. A role described as leading a department, with clinical work mentioned in passing, invites a different question than one describing a caseload with oversight of two therapists. Ask the employer to describe the position the way it will actually be worked, and have counsel review that description before it is finalized.
TN requires a qualifying listed profession, the credential that profession's listing accepts, and prearranged professional employment in the United States for temporary entry. A registered nurse is a listed profession with its own credential rule, a state or provincial licence or a licenciatura degree. The principal should confirm Canadian or Mexican citizenship, a prearranged role in a listed USMCA profession, and the occupation-specific qualification; permanent residence in Canada cannot substitute for citizenship. Bring the licence record, but also bring a duties description that a practising engineer would recognize as engineering.